MANGE

Meaning

A skin disease of mammals caused by parasitic mites (Sarcoptes spp., Demodecidae spp.).

MANGE as a word-puzzle answer

MANGE is a 5-letter word with 2 vowels (A, E) and 3 consonants (M, N, G). Every letter is distinct, so it rarely punishes a clean opening guess.

It leans on high-frequency letters (A, N, E), so a strong vowel-and-common-consonant opener tends to light up quickly. There are no rare letters here, so it is a fair, mid-difficulty answer for the daily Classic puzzle.