BISON

Meaning

A wild ox, Bison bonasus.

BISON as a word-puzzle answer

BISON is a 5-letter word with 2 vowels (I, O) and 3 consonants (B, S, N). Every letter is distinct, so it rarely punishes a clean opening guess.

It leans on high-frequency letters (I, S, O, N), so a strong vowel-and-common-consonant opener tends to light up quickly. There are no rare letters here, so it is a fair, mid-difficulty answer for the daily Classic puzzle.